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Neuroleptic from the group of buy dianabol butyrophenone. It has expressed antipsychotic effect due to blockade of depolarization or decrease the degree of excitation of dopamine neurons (reduction of the release) and postsynaptic blockade (D2) receptors.

It has a mild tranquilizing effect associated with the competitive blockade of postsynaptic dopamine (D2) receptors in the limbic dopaminergic structures of the cerebral cortex and increased metabolism of dopamine in the brain. It has strong antiemetic effect. Blockade of dopamine receptors in dopamine ways black striped substance contributes to the development of extrapyramidal motor reactions; the blockade of dopamine receptors in tuberoinfundibular system causes a decrease in the release of growth hormone and an increase in the release of prolactin by the pituitary gland. There are also some manifestations of the blockade of the alpha-adrenergic receptors of the autonomic nervous system.


When administered haloperidol absorption is 60%, the maximum concentration of active ingredient is achieved after 3-6 h plasma distribution at a stable volume concentration is 18 l / kg, protein binding -. 92%. Haloperidol active undergoes biotransformation in the liver. The half-life when administered averages 24 h (12-37 h). About 40% of a single dose is excreted in the urine within 5 days, and 1% unchanged; 15% is excreted in the faeces. Clearance averages 12 ml / kg / min.


  • acute and chronic psychotic disorders, including schizophrenia, manic-depressive, epileptic, alcoholic psychoses;
  • pronounced behavioral disorders in elderly and childhood;
  • Gilles de la Tourette syndrome;
  • children with autism;
  • Huntington’s chorea;
  • uncontrollable vomiting;
  • prevention and treatment of nausea and buy dianabol vomiting associated with chemotherapy


Adults and adolescents at the beginning of treatment prescribed an average of 500 mg 2-3 times / day. If necessary, taking into account the tolerance dose is gradually adjusted. The maximum dose for adults is 100 mg / day.

Children aged 3-5 years are designated 1/4 dose, aged 6-15 years – half the adult dosage. Children aged 3-12 years of age or with body weight of 15-40 kg at the beginning of psychotic disorders, treatment administered in a dose of 50 mg / kg / day in 2-3 doses. If necessary in view of portability and the daily dose increased to 500 mg at one time 5-7 days until a dose of 150 mg / kg / day.

When violations of conduct and syndrome of Gilles de la Tourette’s and early treatment administered at a dose of 50 mcg / kg / day in 2-3 divided doses. If necessary in view of portability and the daily dose increased to 500 mg at one time 5-7 days until a dose of 75 mg / kg / day. To avoid sedation during the day, sometimes it is recommended to appoint an initial daily dose at bedtime. When the children’s autism drug is prescribed in a dose of 25 mcg / kg / day, if necessary, gradually increase the dose to 50 mg / kg / day.

Patients older appoint 0.5-2 mg 2-3 times / day. If necessary buy dianabol in view of portability and gradually increase the dose.

Side effect

Perhaps: akathisia (can be manifested within the first 6 h after administration of the drug); dystonic extrapyramidal disorder (most often observed in children and young patients, as well as at the beginning of treatment, within 24-48 hours after discontinuation of the drug these symptoms may subside); parkinsonian extrapyramidal disorders (most often seen in elderly patients, symptoms may occur during the first few days of treatment or after long-term treatment and re-occur even after a single dose).

Occasionally: allergic reactions, antiholinergicheskne effects, reduction of fluid intake, unusual tiredness or weakness, orthostatic hypotension, persistent tardive dyskinesia (more common in older patients, women and patients with brain lesions; may persist after discontinuation of haloperidol).

Rare: agranulocytosis, heat stroke, obstructive jaundice, neuroleptic malignant syndrome, tardive dystonia.


  • TSHS disease accompanied by symptoms of pyramidal and extrapyramidal disorders;
  • severe toxic CNS depression caused by drugs;
  • depression;
  • hysteria;
  • pregnancy;
  • lactation (breastfeeding);
  • Hypersensitivity to preparaty

special instructions

Haloperidol-acre should be used with caution in cardiovascular disease events with decompensation, violations conductivity infarction, severe kidney disease.

The drug is not recommended for children under 3 years, due to an increased risk of extrapyramidal reactions.

Drowsiness and parkinsonism symptoms spontaneously cease dose reduction or temporary discontinuation of treatment. In the case of tardive dyskinesia should gradually reduce the dose of haloperidol-Acre and appoint another drug.

There are reports about the possibility of the onset of symptoms of diabetes insipidus, acute glaucoma, trends (long-term treatment) to develop limfomonotsitoza. Elderly patients usually require a smaller initial buy dianabol dose and more gradual titration. For this group of patients is characterized by a high probability of extrapyramidal disorders. To detect early signs of tardive dyskinesia is recommended careful monitoring of the patient. The treatment of neuroleptic malignant syndrome, neuroleptic development is possible at any time, but it occurs most often soon after the beginning of therapy or when the patient’s transfer from one to another antipsychotic agent, during combination treatment with other psychotropic drugs or after a dose increase.

Patients receiving haloperidol-acre, should refrain from activities potentially hazardous activities that require increased attention and rapid psychomotor reactions. The period of application of haloperidol-acre prohibited from drinking alcoholic beverages.

Drug interactions

Haloperidol-acre potentiates the effect of antihypertensive drugs, opioids, barbiturates, ethanol and ethanol-preparations. While the use of epinephrine may develop its blockade of the alpha-adrenergic action, which may lead to severe hypotension and tachycardia.

With simultaneous application of haloperidol-Acre with other buy dianabol drugs that cause extrapyramidal reactions, may increase the frequency and severity of their development.

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